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phentermine 37mg works by stimulating the release of certain chemicals in the brain that help control hunger, leading to reduced appetite and helping people eat less. Phentermine is typically taken once a day, often in the morning before breakfast or 1–2 hours after eating, to avoid interfering with sleep. While it can be effective for short-term weight loss, it is usually prescribed for a few weeks in combination with a healthy diet and exercise. Common side effects include dry mouth,